An ameloblastic fibroma is a fibroma of the ameloblastic tissue, that is, an odontogenic tumor arising from the enamel organ or dental lamina. It may be either. Ameloblastic fibroma, is a mixed odontogenic tumor, which commonly affects young children under the age of 20 years, with the mandibular premolar-molar. ameloblastic fibroma in a 9-year-old boy has been presented along with a review of the literature. The tumor responded to conservative surgical treatment.

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Received Jan 24; Accepted Jun 6. Thin septa were observed within lesion. The swelling caused labial and buccal cortical expansion bilaterally and extended up to the pterygoid plates along with palatal bone thickening.

Pathology Outlines – Benign tumors / tumor-like conditions: ameloblastic fibroma

Hyaline-like tissue is also seen adjacent to the epithelial strands and islands [ Figure 2 ]. To conclude, we report a rare case of AF with high cellularity.

Grossly, ameloblastic fibroma appears as firm, lobular soft fiibroma mass with a smooth surface [ 3 ]. Ameloblastic sarcoma of the mandible. Enucleation of the tumor was performed, followed by curettage of the surrounding bone.

Radiographic exams should always be requested to complement the periodic clinical exam because several mandibular lesions may present as an incidental radiographic finding.

Case Reports in Pediatrics. In contrast to conventional ameloblastoma, the strands of AFs show double or triple layer of cuboidal cells.

Profile picture of the patient showing the asymmetry flbroma to the swelling Click here to view. If a tooth is associated with the lesion it may accompany the specimen. The nature of AF still stands enigmatic, as there has been a long debate as to whether ameloblastic fibroma represents a hamartomous growth or is a true benign neoplasm.


Incidence of Maxillary AF is believed to be uncommon by itself; its bilateral presentation is exceedingly rare. Abstract Ameloblastic fibroma AF is a benign tumor of mixed odontogenic origin, which affects predominantly young individuals. Microscopically AFs are composed of both the epithelial and connective tissue components; the later appears to recapitulate dental papilla made akeloblastic of spindled and angular cells with delicate collagen, imparting a myxomatous appearance.

An impacted tooth may be associated with the tumor in approximately three quarters of the cases [ 256 qmeloblastic.

The occurrence ameloblqstic similar cases of AF is very rare 4. We herein describe a massive AF involving mandible in a year-old female patient, suggestive of the neoplastic variant, with a special reference to its aspiration cytologic findings.

Both the wmeloblastic exhibited gradual increase in size with evidence of nasal blockage Figure 1. Ameloblastic fibroma, ameloblastic fibro-odontoma, and odontoma. Braz Dent J ; This underscores the inestimable value of access to periodic dental exams, especially radiographic exams among children and adolescents. The lesion was excised and curettage of the adjacent maxillary bone was performed under general anesthesia.

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Int J Oral Maxillofac Ameloblastiic ;2: Mitoses should not be a feature of ameloblastic fibroma [ 13 ]. On examination, the swellings were diffuse extending on to the zygomatic arch, nontender with no secondary changes.

Although the epithelium-poor odontogenic fibroma present a loose connective tissue, with a fibromyxoid appearance in some areas, the epithelial islands are inactive and scarce 6. However, recent reports have suggested that this lesion has the potential for recurrence and malignant transformation.

Histological evaluation revealed multiple fragments of richly cellular mesenchymal tissue containing round drop-like islands and long narrow anastomosing cords of odontogenic epithelium. Radiographically, AF appears as a well-defined, unilocular or multilocular radiolucent lesion, ameloblqstic sclerotic radiopaque margins 34. In neoplastic cases, it may be labeled an ameloblastic fibrosarcoma in accord with the terminological distinction that reserves the word fibroma for benign tumors and assigns the word fibrosarcoma to malignant ones.


Case Report A year-old male was referred for evaluation of a lesion in the left body of the mandible identified in a radiographic exam for aneloblastic treatment planning. Ameloblastic fibroma, differential diagnosis, incidental finding, mixed image, radiographic features. Basic Oral and Maxillofacial Pathology. On radiographs, smaller lesions are well circumscribed and unilocular with a sclerotic border, while larger ones are multilocular.

Open in a separate window. Aspiration cytology of ameloblastic fibroma: This article about a neoplasm is a stub. The overlying mucosa was intact. J Clin Exp Dent. The epithelial component is arranged in thin branching cords or small nests with scanty cytoplasm and basophilic nuclei, while stellate reticulum like cells are common in larger nests. The medical history revealed no prior trauma or episodes of pain in the affected region.

The epithelial islands, nests, and strands were composed of peripheral tall columnar hyperchromatic cells exhibiting reversal of polarity and loosely arranged central cells having angular to spindle shape. Herein, we report the first case of a bilateral maxillary ameloblastic fibroma in a 2-year-old female child patient who presented with a chief complaint of swelling in the right mid facial region.

Although rare, AF should be also considered in the differential diagnosis of mixed radiographic images of the jaws in young patients. Several spindle-shaped cells and abundant extracellular matrix fibrlma were found between the islands of neoplastic cells HE, x Benign Tumors of the Jaws.