APIDRA PI PDF

PI & CMI Trade Names and Active Ingredients containing insulin glulisine. 1 Documents available. Need more information on a Apidra, CMIPI, Insulin glulisine. PI & CMI Trade Names and Active Ingredients containing insulin. 42 Documents Actrapid, PI, Insulin – human (human insulin) Apidra, CMIPI, Insulin glulisine. Apidra PI MKT. #v Page 1. PRODUCT INFORMATION. APIDRA APIDRA [insulin glulisine injection {rDNA origin}] is a recombinant human insulin .

Author: Garan Goltinris
Country: El Salvador
Language: English (Spanish)
Genre: Literature
Published (Last): 6 April 2005
Pages: 322
PDF File Size: 9.76 Mb
ePub File Size: 14.62 Mb
ISBN: 667-2-18099-536-7
Downloads: 95733
Price: Free* [*Free Regsitration Required]
Uploader: Tojanris

Pull the needle out of the Apidra vial. Draw air into a U insulin syringe equal to the dose of Apidra to be injected.

If bubbles are present, hold the syringe vertically needle pointed upwards and tap firmly until the bubbles float to the top. Ask your doctor, pharmacist or diabetes educator to answer any questions you may have. Optimized basal-bolus insulin regimens in type 1 diabetes: Upon registration, patient receives all program details. Timing of meal insulin boluses to achieve optimal postprandial glycemic control in patients with type 1 diabetes.

Your dose of Apidra or other medicines may need to be changed. Parent report of mealtime behavior and parenting stress in young children with type 1 diabetes and in healthy control subjects. Discard the pre-filled pen within 28 days of first use.

Study of the insulin dimerization: Your blood sugar level may become high hyperglycaemia. This is the best way to tell if your diabetes is being controlled properly. Few studies have compared the rapid-acting insulin analogs in this population but limited data indicate that glulisine is as effective as lispro when used in a basal—bolus regimen.

Do not skip meals while using Apidra. What is in this leaflet This leaflet answers some common questions about Apidra. Heise T, Heinemann L. Your doctor or diabetes educator will show you how and when to do this.

  CRIMINAL MINDS SOCIOPATHS SERIAL KILLERS AND OTHER DEVIANTS PDF

The role of insulin glulisine to improve glycemic control in children with diabetes mellitus

Draw air into a U insulin syringe equal to the dose of cloudy NPH insulin you are using. Pre-filled disposable pens Apidra SoloStar disposable pens are pre-filled and ready for use. Consider dosage apicra or discontinuation of TZD if heart failure occurs.

If you have not told your doctor about any of the above, tell them before you start using Apidra. Storage All medicines should be kept where children cannot reach them. Management of children with type 1 diabetes has seen a shift in favor of mimicking normal physiological insulin responses with multiple daily injections or continuous subcutaneous insulin infusions CSII.

Glulisine has also been shown to be more prone than aspart to form insoluble insulin fibrils, which are not biologically potent. Change insulin regimens cautiously and only under medical supervision.

This is because you could choke. Diet and low calorie soft drinks do NOT contain sugar and are unsuitable to take for hypoglycaemia. Ask your doctor, pharmacist or diabetes educator for help.

Certain heart medications, especially beta-blockers, may mask the symptoms of hypoglycaemia. Other adverse effects When glulisine was compared with RHI in a small crossover trial in 10 adolescents and 10 children with type 1 diabetes, no safety concerns arose. Aspart is homologous to RHI except for the substitution of proline for aspartic acid at B28 Figure 4. Several large trials have studied glulisine in adult patients with type 1 and type 2 diabetes, but data in the pediatric population aapidra limited.

How long to use Apidra Continue using Apidra for as long as your doctor recommends. This emphasizes the desirability of attaining and maintaining excellent glycemic control from the time of diagnosis. To date no data are available see Table 4. Medicines that may increase the blood sugar lowering effect of Apidra pk. The second clinical study, which included adolescents and adults, was a crossover trial looking at timing of meal-related glulisine bolus administration via CSII in 23 subjects.

  ALAN GUTH INFLATIONARY UNIVERSE PDF

Slowly count to 10 before removing the needle from the skin. Tolerability Flexibility of apira In general, use of rapid-acting insulin analogs gives greater flexibility for the timing of injections, especially important for children and teenagers.

Comparison of insulin lispro with regular human insulin for the treatment of type 1 in adolescents. Apidra is a modified insulin that is very similar to human insulin. Apidra helps most people with diabetes, but it may have unwanted side effects in a few people. The trend persisted when children and adolescents were analyzed separately see Table 3. Inject the full dose of Apidra, or Apidra mixed with NPH insulin, by pushing the plunger as far as it will go.

The dimer and hexameric forms of human insulin confer conformational stability and are less likely to denature in storage. Short acting inuslin analogs versus regular human insulin in pateints with daibetes mellitus. Paidra is very important that you manage your diabetes pii.

Be careful not to let your blood sugar levels fall too low. If you have trouble eating solid foods, use sugar-sweetened drinks as a carbohydrate substitute or eat small amounts of bland food. If you miss a dose – Hyperglycaemia If you forget to take your insulin dose check your blood sugar level as soon as possible.

The role of insulin glulisine to improve glycemic control in children with diabetes mellitus

Do not be alarmed by the following lists of side effects. This review appraises the current available studies and reviews on insulin glulisine in children.

A quality-of-life assessment of intensive insulin therapy using insulin lispro switched from short-acting insulin and measured by an ITR-QOL questionnaire: