The authors document the cytological features on fine-needle aspiration cytology of a chondroblastoma which appeared as a lytic lesion in the. Chondroblastoma is an uncommon benign cartilage producing neoplasm with a characteristic epiphyseal location. This report documents the. Chondroblastoma is a rare primary bone tumor of young people .. Fine needle aspiration cytology of chondroblastoma of bone. Cancer.

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In chondromyxoid fibroma, the smears are sparsely cellular and lack the mononuclear cell component.

A year-old male presented with pain and diffuse swelling on the knee joint since 2 months. Armed Forces Institute of Pathology; Grossly, the specimen consisted of multiple irregular grey-brown chondroblastomq bits with areas of hemorrhage.

Iowa Orthop J ; Ipsilateral inguinal lymphadenopathy was not demonstrable. However, chondrosarcoma characteristically shows fragments of hyaline cartilage and cells sitting in the lacuna. In eight cases, diagnosis was rendered preoperatively.

Giant chondroblastoma chondroblqstoma the scapula with pulmonary metastases. National Center for Biotechnology InformationU. Chondroblastoma of the skull and facial bones.

At cytology, other giant cell-rich tumors and tumorlike lesions such as aneurysmal bone cyst ABCgiant cell tumor, and chondromyxoid fibroma fall under the differential diagnosis of chondroblastoma. The cells were oval, spindle to stellate with small oval nuclei and uniform dense chromatin.

Fine needle aspiration cytology of chondroblastoma of the fibula

Chondroblastoma with aneurysmal bone cyst formation. In addition to chondroblastoma, ABC can occur secondarily in giant cell tumor and osteosarcoma. Fine-needle aspiration cytology FNAC is an established cost-effective diagnostic tool for skeletal lesions. Sitemap What’s New Feedback Disclaimer. However, it is unclear whether malignant CMF actually exists or whether it represents another type of sarcoma that has been misdiagnosed. Chondromyxoid fibroma closely mimics chondroblastoma due to the presence of myxoid background substance, chondroid fragments and osteoclastic giant cells; however, its spindle-shaped or stellate, fibroblast-like tumour cells in contrast to cytoloy mononuclear cells of chondroblastoma with distinct cell borders, round-to-oval nuclei and dense eosinophilic cytoplasm help in differentiating cytolgy two entities.


Home About Us Advertise Amazon. Open in a separate window. Other giant cell containing lesions that comes under differential diagnosis includes osteoclastoma that involves epiphyses of long bones, but the chondroid differentiation and chicken-wire pattern of calcification on HPE, the osteoclastic giant cells are large, more numerous than chondroblastoma cytoloyg attached to the periphery of the clustered spindle cells, and the nuclei of mononuclear and chondorblastoma giant cells present identical morphological features; however, in contrast, the nuclei of chondroblasts differ morphologically from the smaller nuclei of osteoclast-like giant cells.

Fine needle aspiration cytology of chondroblastoma of the fibula

chondroblastoam Case 2 A year-old male presented with diffuse swelling on the shoulder joint of 1-month duration. Despite this, we have a limited case series describing FNAC findings in chondroblastoma.

Histopathology revealed tumor composed of sheets of polyhedral chondroblasts with round to ovoid, indented and lobulated nuclei and thick sharply defined cell membrane. Diagnosis of chondroblastoma was made on cytology. There is associated cortical destruction with sotissue components. Please review our privacy policy. Report of a case and review of literature. Fine needle aspiration cytology in the management of tumors and tumorlike lesions of bone.


No mitotic figures were seen. Cytological findings of CMF have appeared in only a few reports so far. The cells were of variable sizes and shapes and were mostly dispersed singly in myxoid background [Figure – 2].

Cytological diagnosis of chondroblastoma: diagnostic challenge for the cytopathologist

None, Conflict of Interest: The cellular elements comprise a variable mixture of spindle cells, stellate cells and chondroblasts with nuclear pleomorphism but with uniformly bland, smudgy chromatin and no mitotic figures. In three cases, the diagnosis was missed on FNAC, among which, one was associated with ABC and in another case an erroneous diagnosis of a giant cell tumor was made. Diagnosis of chondroblastoma was made on cytology. Aggressive scapular chondroblastoma with secondary metastasis: Eur J Med Res.

Footnotes Source of Support: Aggressive scapular chondroblastoma with secondary metastasis: At cytology, the presence of giant cells, chondroid matrix, mononuclear cells with nuclear indentation, and grooving along with glassy, vacuolated cytoplasm are characteristic of chondroblastoma.